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Localization of Cu/Zn-SOD and Mn-SOD in the rat cochlea.

作者信息

Rarey K E, Yao X

机构信息

Department of Anatomy & Cell Biology, College of Medicine, University of Florida, Gainesville 32610, USA.

出版信息

Acta Otolaryngol. 1996 Nov;116(6):833-5. doi: 10.3109/00016489609137935.

DOI:10.3109/00016489609137935
PMID:8973716
Abstract

Distributions of the copper/zinc-superoxide dismutase (Cu/Zn-SOD) and the manganese superoxide dismutase (Mn-SOD) in the rat cochlea were studied by immunohistochemistry with specific polyclonal antibodies to Mn-SOD and Cu/Zn-SOD. Coexpression of Mn-SOD and Cu/Zn-SOD was observed in the cochlear tissues with differing immunoactivity intensities. The presence of Cu/Zn- and Mn-SOD implies the existence of a defense system against free oxygen radical (FOR) injury in cochlear tissues.

摘要

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