Nagano T, Konya E, Imanishi M, Akiyama T, Kurita T
Department of Urology, Kinki University School of Medicine.
Hinyokika Kiyo. 1996 Nov;42(11):883-5.
A case of renal cell carcinoma of the right native kidney following cadaveric renal transplantation is reported. A 44-year old male underwent cadaveric renal transplantation in 1993 and had stable graft function, but he had suffered from hypertension before the renal transplantation and multiple antihypertensive medications were not effective. Abdominal computed tomography demonstrated bilateral contracted kidneys, but we could not rule out renal cell carcinoma of the right kidney, completely. Angiography of the graft artery revealed no stenosis and venous sampling suggested that plasma renin activity was increased in the left renal vein. Thus we performed bilateral native nephrectomy. Histology of the right kidney was renal cell carcinoma, clear cell subtype, grade 1, pT2, and the left kidney was end stage of renal disease. Because of high incidence of malignant neoplasia after renal transplantation, routine careful examination is quite important.
本文报告一例尸体肾移植后右侧原肾发生肾细胞癌的病例。一名44岁男性于1993年接受尸体肾移植，移植肾功能稳定，但他在肾移植前患有高血压，多种抗高血压药物治疗无效。腹部计算机断层扫描显示双侧肾脏萎缩，但我们不能完全排除右侧肾癌。移植肾动脉血管造影显示无狭窄，静脉采血提示左肾静脉血浆肾素活性升高。因此，我们进行了双侧原肾切除术。右侧肾脏组织学检查为肾细胞癌，透明细胞亚型，1级，pT2，左侧肾脏为终末期肾病。由于肾移植后恶性肿瘤的发生率较高，常规仔细检查非常重要。
