Soengas J L, Strong E F, Fuentes J, Aldegunde M, Andrés M D
Area de Fisioloxía Animal, Facultade de Ciencias, Universidade de Vigo, Spain.
Rev Esp Fisiol. 1996 Sep;52(3):131-42.
A study of several pathways of carbohydrate and ketone bodies metabolism was carried out in Atlantic salmon (Salmo salar) to assess the basal metabolism of the brain, and the possible existence of post-feeding changes in brain and liver metabolism. The main results obtained in brain of Atlantic salmon indicate a use of exogenous glucose as a main fuel source since important hexokinase activities were noticed, and brain glycogen levels were usually very low. Several post-feeding changes were observed in brain including an apparent decrease in glycolytic potential, as well as a decreased use of ketone bodies. In contrast, no major post-feeding changes were detected in liver metabolism. A role for ketone bodies as a metabolic fuel in brain of Atlantic salmon is supported by both the high levels of acetoacetate found in brain, and the presence of an active beta-hydroxybutyrate dehydrogenase.
对大西洋鲑鱼（Salmo salar）的碳水化合物和酮体代谢的几种途径进行了研究，以评估大脑的基础代谢，以及喂食后大脑和肝脏代谢变化的可能性。在大西洋鲑鱼大脑中获得的主要结果表明，外源性葡萄糖是主要的燃料来源，因为观察到重要的己糖激酶活性，并且大脑糖原水平通常非常低。在大脑中观察到了几种喂食后的变化，包括糖酵解潜能明显降低以及酮体利用减少。相比之下，在肝脏代谢中未检测到主要的喂食后变化。大脑中发现的高水平乙酰乙酸以及活性β-羟基丁酸脱氢酶的存在，都支持了酮体在大西洋鲑鱼大脑中作为代谢燃料的作用。
