Soyka M, Sass H
Psychiatric Hospital, University of Munich, Germany.
Alcohol Alcohol Suppl. 1994;2:531-6.
The efficacy of the homotaurine-derivative acamprosate (calcium acetylhomotaurinate) to increase abstinence rates in weaned alcoholics was examined in a placebo-controlled double-blind multicentre study involving 272 subjects. Preliminary results indicate a significantly higher abstinence rate during and at the end of the study (42.8% vs. 20.7%, p < 0.01), a higher number of abstinent days and a lower drop-out rate in the treated than in the placebo group.
在一项涉及272名受试者的安慰剂对照双盲多中心研究中，对同型牛磺酸衍生物阿坎酸（乙酰同型牛磺酸钙）提高戒酒者戒酒率的疗效进行了研究。初步结果表明，在研究期间及结束时，戒酒率显著更高（42.8%对20.7%，p<0.01），戒酒天数更多，且治疗组的脱落率低于安慰剂组。
