Suppr超能文献

[摩洛哥的衣原体感染与男性不育症]

[Chlamydial infections and male infertility in Morocco].

作者信息

Radouani F, Bennani A, Takourt B, Hda N, Ibrahimi S, Boutaleb Y, Guinet R, Benslimane A

机构信息

Laboratoire des Chlamydiae, Institut Pasteur du Maroc, Casablanca, Maroc.

出版信息

Contracept Fertil Sex. 1996 Oct;24(10):779-83.

PMID:8974617
Abstract

Chlamydia trachomatis infection of the lower genital is recognised as the most common sexually transmitted disease, is role in male infertility is controversial, the objective of this study was to evaluate the part that this pathogen agent takes in male infertility among maroccan population, to compare serological tests, sperm abnormalities, antisperm-antibodies and DNA research in semen. Microimmunofluorescence (MIF) was done for 139 patients, 124 were checked for sperm abnormalities, 87 for antisperm-antibodies and 92 for DNA research in sperm. The results showed that MIF is positive in 24,5%, 11% of the subjects in antisperm antibodies, 8% of them simultaneously in anti-Chlamydia and antisperm antibodies and 5 of them had sperm abnormalities. Azoospermy was more observed in positives subjects in Chlamydia trachomatis antibodies. C. trachomatis DNA was found in 7,6% and there was no association between the detection of C. trachomatis in semen specimens and the presence of anti-Chlamydia trachomatis, antibodies in serum. We conclude that, because of the complexity of the Chlamydia's physiopathology, association between several tests is necessary in male infertility workup.

摘要

沙眼衣原体引起的下生殖道感染被认为是最常见的性传播疾病,其在男性不育症中的作用存在争议。本研究的目的是评估这种病原体在摩洛哥人群男性不育症中所起的作用,比较血清学检测、精子异常、抗精子抗体和精液中的DNA检测情况。对139名患者进行了微量免疫荧光检测(MIF),对124名患者检查了精子异常情况,对87名患者检测了抗精子抗体,对92名患者进行了精子DNA检测。结果显示,MIF检测阳性率为24.5%,抗精子抗体检测阳性率为11%,其中8%的患者同时存在抗衣原体和抗精子抗体,5名患者存在精子异常。在沙眼衣原体抗体检测呈阳性的患者中,无精子症更为常见。在7.6%的患者精液中发现了沙眼衣原体DNA,精液标本中沙眼衣原体的检测与血清中抗沙眼衣原体抗体的存在之间没有关联。我们得出结论,由于衣原体生理病理学的复杂性,在男性不育症检查中需要多种检测方法联合使用。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验