Lippert S, Böck M, Rahrig S, Kreutzmann H, Heim M U
Institut für Transfusionsmedizin und Immunhämatologie, Universität Magdeburg, Deutschland.
Beitr Infusionsther Transfusionsmed. 1996;33:117-20.
It has been well established that cryopreservation of red cells with glycerol is a suitable method for long-time storage. Therefore, many data for quality control have been published. Most measurements, however, are restricted to the final product. Less information is available about the particular steps of cryopreservation. The present paper describes in detail the results of quality control measurements during the procedure. Although the final product meets the demand of the WHO for cryopreserved red cells, it could be demonstrated that erythrocytes are remarkably damaged by the deep-freezing process. Further experiments seem to be necessary in order to improve the details of the deep-freezing procedure.
甘油冷冻保存红细胞是一种适合长期储存的方法，这一点已经得到充分证实。因此，已经发表了许多质量控制数据。然而，大多数测量仅限于最终产品。关于冷冻保存的具体步骤的信息较少。本文详细描述了该过程中质量控制测量的结果。尽管最终产品符合世界卫生组织对冷冻保存红细胞的要求，但可以证明红细胞在深度冷冻过程中受到了显著损伤。为了改进深度冷冻程序的细节，似乎有必要进行进一步的实验。
