Rosbotham J L, Corbett E L, Grant H R, Hay R J, Bryceson A D
St John's Institute of Dermatology, Guy's Hospital, London, UK.
Clin Exp Dermatol. 1996 Jul;21(4):288-90. doi: 10.1111/j.1365-2230.1996.tb00097.x.
We report a case of mucocutaneous leishmaniasis in a otherwise fit Caucasian man who had traveled in an endemic area. Initial tissue microscopy failed to identify the causative organism, which was only determined by subsequent culture as Leishmania braziliensis. This case illustrates the variability in the presence of Leishman-Donovan (LD) bodies in histopathological studies and emphasizes the need for culture in suspected cases of leishmaniasis, particularly given the ability of certain Leishmania species such as L. braziliensis to cause recalcitrant and destructive infections of the nose and mouth.
我们报告一例皮肤黏膜利什曼病病例,患者为一名身体健康的白种男性,曾前往该病流行地区。最初的组织显微镜检查未能识别出致病生物体,后来通过培养才确定为巴西利什曼原虫。该病例说明了在组织病理学研究中利什曼-多诺万(LD)小体存在情况的变异性,并强调在疑似利什曼病病例中进行培养的必要性,特别是考虑到某些利什曼原虫物种(如巴西利什曼原虫)能够引起顽固且具有破坏性的鼻口部感染。