Wierrani F, Zoubek A, Grin W, Kronberger M, Preiser J, Gabriel C, Bibus B, Koscielniak E, Gadner H, Grünberger W
Gynäkologische & Geburtshilfliche Abteilung, Krankenanstalt Rudolfstiftung, Wier.
Geburtshilfe Frauenheilkd. 1996 Aug;56(8):441-2. doi: 10.1055/s-2007-1023262.
Although rare, sarcoma botryoides of the vagina in infants is a highly aggressive soft tissue tumour. Former opinions suggesting exenterative surgery and radiation to improve the dismal outcome in these young children, are outdated. Due to balanced therapies (topical tumourectomy, chemotherapy and radiation adjusted to tumour stage) cure of these sarcomas may be expected dependent on tumour stage, localisation and response to chemotherapy. The rate of complete remissions has increased in recent years. We report on an eighteen-month old girl with complete remission of tumour stage IIA who had been treated according to the CWS 91 protocol. Diagnosis and treatment were performed in March 1994 at the age of six months. We observed the patient in complete remission for 8 months (till September 1995).
尽管婴儿阴道葡萄状肉瘤罕见，但它是一种侵袭性很强的软组织肿瘤。以前认为扩大性手术和放疗可改善这些幼儿的不良预后的观点已过时。由于采用了平衡治疗方法（局部肿瘤切除术、根据肿瘤分期调整的化疗和放疗），有望根据肿瘤分期、部位及对化疗的反应治愈这些肉瘤。近年来完全缓解率有所提高。我们报告一例18个月大的女童，她按照CWS 91方案接受治疗，肿瘤分期为IIA期且已完全缓解。诊断和治疗于1994年3月在患儿6个月大时进行。我们观察到该患者完全缓解了8个月（直至1995年9月）。
