[A derivative of the X(Z) chromosome causes a change in the mutability properties of genes in homologous chromosomes from unstable lines of Drosophila melanogaster].

The impact of an XZ chromosome derivative, the In(1)T2,ymosWYIsnmYI strain, on mutation and reversion frequencies in strains with the unstable yellow gene is analyzed. These strains were isolated during a yellow mutation outbreak observed in the natural population of Drosophila melanogaster in Uman' (Ukraine) from 1982 to 1991. The In(1)T2,YmosWYIsnmYI chromosome was shown to suppress yellow gene mutability and activate singed gene mutability. A possible mechanism of homologous suppression and destabilization is considered.