Salerno A, Georgesco M
Laboratoire d'explorations fonctionnelles neuromusculaires, service de neurologie B, hôpital Cui de Chauhac, Montpellier, France.
Neurophysiol Clin. 1996;26(4):227-35. doi: 10.1016/s0987-7053(96)85004-0.
To assess their interest, we studied different motor evoked potentials (MEP) parameters in 18 amyotrophic lateral sclerosis (ALS) patients and compared them to those obtained in 20 subjects unaffected by neurological diseases: cortical threshold (CT), latency and amplitude of primary responses (PR), central conduction time (CCT), silent period (SP) contralateral to the stimulated cortex and late muscular responses (LMR). In normal subjects MEP parameters were in agreement with those described in the literature, except for LMR. These were only recorded in upper limbs with latencies around 200 ms in 9 out of 20 subjects. In ALS patients, LMR were not modified as compared to normal subjects. Except for mean CCT, in upper and lower limbs, all parameters were altered. We conclude that all MEP parameters are useful in ALS and disclose the involvement of the entire pyramidal tract in this disease.
为评估其兴趣，我们研究了18例肌萎缩侧索硬化症（ALS）患者的不同运动诱发电位（MEP）参数，并将其与20例未患神经系统疾病的受试者所获得的参数进行比较：皮质阈值（CT）、主反应（PR）的潜伏期和波幅、中枢传导时间（CCT）、刺激皮质对侧的静息期（SP）以及晚期肌肉反应（LMR）。在正常受试者中，除LMR外，MEP参数与文献中描述的一致。这些仅在20名受试者中的9名受试者的上肢记录到，潜伏期约为200毫秒。与正常受试者相比，ALS患者的LMR未发生改变。除平均CCT外，上肢和下肢的所有参数均发生改变。我们得出结论，所有MEP参数在ALS中均有用，并揭示了该疾病中整个锥体束的受累情况。
