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[IgA肾病中的尿酸代谢异常]

[Uric acid metabolism abnormalities in IgA nephropathies].

作者信息

Konopielko Z, Zawadzki J, Wyszyńska T

机构信息

Oddział Nefrologii Dializoterapii i Transplantacji Nerek Centrum Zdrowia Dziecka w Warszawie.

出版信息

Pediatr Pol. 1996 Apr;71(4):327-30.

PMID:8975220
Abstract

The possibility of uric acid tract stones forming was analysed in 12 children with IgA nephropathy (group I) and 10 children with other hematuric glomerulopathies (group II). Elevated serum uric acid level and higher urinary excretion was found only in children with IgAN during exacerbation of the disease. Uric acid nephrolithiasis was found only in children with IgA nephropathy. The prophylactic treatment (proper diet, high fluid intake, adjusting urinary pH to 6.5-6.8) was effective in decreasing the number of exacerbations, urinary tract infections and formation of uric acid stones.

摘要

对12例IgA肾病患儿(I组)和10例其他血尿性肾小球病患儿(II组)形成尿酸结石的可能性进行了分析。仅在疾病加重期的IgA肾病患儿中发现血清尿酸水平升高和尿排泄增加。仅在IgA肾病患儿中发现尿酸肾结石。预防性治疗(合理饮食、大量饮水、将尿液pH值调节至6.5 - 6.8)在减少疾病加重次数、尿路感染和尿酸结石形成方面有效。

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