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[IgA肾病中的尿酸代谢异常]

[Uric acid metabolism abnormalities in IgA nephropathies].

作者信息

Konopielko Z, Zawadzki J, Wyszyńska T

机构信息

Oddział Nefrologii Dializoterapii i Transplantacji Nerek Centrum Zdrowia Dziecka w Warszawie.

出版信息

Pediatr Pol. 1996 Apr;71(4):327-30.

PMID:8975220
Abstract

The possibility of uric acid tract stones forming was analysed in 12 children with IgA nephropathy (group I) and 10 children with other hematuric glomerulopathies (group II). Elevated serum uric acid level and higher urinary excretion was found only in children with IgAN during exacerbation of the disease. Uric acid nephrolithiasis was found only in children with IgA nephropathy. The prophylactic treatment (proper diet, high fluid intake, adjusting urinary pH to 6.5-6.8) was effective in decreasing the number of exacerbations, urinary tract infections and formation of uric acid stones.

摘要

对12例IgA肾病患儿(I组)和10例其他血尿性肾小球病患儿(II组)形成尿酸结石的可能性进行了分析。仅在疾病加重期的IgA肾病患儿中发现血清尿酸水平升高和尿排泄增加。仅在IgA肾病患儿中发现尿酸肾结石。预防性治疗(合理饮食、大量饮水、将尿液pH值调节至6.5 - 6.8)在减少疾病加重次数、尿路感染和尿酸结石形成方面有效。

相似文献

1
[Uric acid metabolism abnormalities in IgA nephropathies].[IgA肾病中的尿酸代谢异常]
Pediatr Pol. 1996 Apr;71(4):327-30.
2
[Uric acid metabolism in patients with chronic glomerulonephritis].[慢性肾小球肾炎患者的尿酸代谢]
Nihon Jinzo Gakkai Shi. 1989 Sep;31(9):941-50.
3
Evidence of enhanced uric acid clearance in macrohematuric patients with IgA nephropathy: prognostic significance of macrohematuria.IgA 肾病大量血尿患者尿酸清除率增加的证据:大量血尿的预后意义。
Clin Nephrol. 1990 Jan;33(1):41-6.
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Urinary calculi associated with purine metabolism. Uric acid nephrolithiasis.与嘌呤代谢相关的尿路结石。尿酸肾结石。
Endocrinol Metab Clin North Am. 1990 Dec;19(4):821-38.
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[A case of renal hypouricemia associated with IgA nephropathy--with special reference to changes in serum uric acid and uric acid clearance in a clinical course exceeding 15 years].[1例与IgA肾病相关的肾性低尿酸血症——特别提及超过15年临床病程中血清尿酸及尿酸清除率的变化]
Nihon Jinzo Gakkai Shi. 1994 Mar;36(3):277-83.
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[Sodium excretion in children with lithogenic disorders].[患有结石形成疾病儿童的钠排泄]
Srp Arh Celok Lek. 1998 Sep-Oct;126(9-10):321-6.
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Uric acid correlates with the severity of histopathological parameters in IgA nephropathy.尿酸与IgA肾病组织病理学参数的严重程度相关。
Nephrol Dial Transplant. 2005 Jan;20(1):89-95. doi: 10.1093/ndt/gfh584. Epub 2004 Nov 30.
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Ambulatory blood pressure, proteinuria and uric acid in children with IgA nephropathy and their correlation with histopathological findings.IgA肾病患儿的动态血压、蛋白尿和尿酸及其与组织病理学结果的相关性。
Kidney Blood Press Res. 2008;31(5):337-42. doi: 10.1159/000164800. Epub 2008 Oct 22.
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[Pulse pressure and circadian blood pressure profile in children with IgA nephropathy and Shoenlein-Henoch nephropathy].[IgA肾病和过敏性紫癜性肾炎患儿的脉压与动态血压曲线]
Pol Merkur Lekarski. 2009 Apr;26(154):281-5.
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Local factors compared with systemic factors in the formation of bladder uric acid stones.膀胱尿酸结石形成中局部因素与全身因素的比较
Urol Int. 2009;82(1):48-52. doi: 10.1159/000176025. Epub 2009 Jan 20.

引用本文的文献

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An evaluation of the roles of hematuria and uric acid in defining the prognosis of patients with IgA nephropathy.血尿和尿酸在IgA肾病患者预后判定中的作用评估
Pediatr Nephrol. 2022 May;37(5):947-958. doi: 10.1007/s00467-021-05092-x. Epub 2021 May 13.
2
Hyperuricosuria, hematuria, and novel bladder images with IgA nephropathy.高尿酸尿症、血尿以及IgA肾病的新型膀胱影像表现。
Proc (Bayl Univ Med Cent). 2020 Dec 23;34(2):294-296. doi: 10.1080/08998280.2020.1860428.