Stillger E, Persigehl M, Frik W
Rontgenblatter. 1977 Aug;30(8):414-20.
Forty-three cholangio-cholecystographies were carried out with iotroxamide. A the same time, the behavior of various serum enzymes was controlled. Iotroxamide satisfactorily demonstrated the biliary tract for the diagnosis in 37 of our patients (86.5%). Only an inadequate or incomplete evaluation was possible for 6 of our patients (13.5%). Due to the pharmacokinetic characteristics of iotroximide, the time-density ratio is very favorable. As a result, the contrast radiograph of the biliary tract including the gallbladder was available for evaluation as early as 30 minutes after the infusion and almost always within 60 minutes. Minor subjective side effects were observed in only 4 cases. With the exception of 2 cases with obstructed bile flow, the serum-enzyme level was not significantly altered after administration of the contrast medium.
使用碘曲仑进行了43次胆管胆囊造影。与此同时,对各种血清酶的变化进行了监测。碘曲仑在37例患者(86.5%)中对胆道的诊断显示效果良好。仅6例患者(13.5%)出现评估不充分或不完全的情况。由于碘曲仑的药代动力学特性,时间-密度比非常有利。因此,早在输注后30分钟即可获得包括胆囊在内的胆道造影照片以供评估,几乎总是在60分钟内。仅4例观察到轻微的主观副作用。除2例胆汁流动受阻的病例外,给予造影剂后血清酶水平无明显变化。