Hashimoto Y, Kimura K, Hirano T, Uchino M, Ando M
Department of Neurology, Kumamoto City Hospital.
Rinsho Shinkeigaku. 1996 Sep;36(9):1100-3.
Among 43 adult patients with meningitis, 8 (18.6%) had cerebral infarction associated with meningitis during their clinical course. The total number of cerebral infarctions was 18. In 4 patients of good outcome (ambulatory in 3 cases and wheelchair in 1 case) with a mean age of 39 years, the number of cerebral infarctions was 1 per patient, and did not increase. In 4 patients of poor outcome (vegetative in 2 cases and died in 2 cases) with a mean age of 68 years, the number of cerebral infarctions was 1 in two cases and 2 in two cases, and later increased in 3 of the cases. Locations of cerebral infarctions were 3 in the striatocapsular lesion, 1 in the posterior limb of internal capsule, 1 in the middle cerebral artery territory, 5 in the tuberothalamic artery territory, 5 in the capsular genu, 1 in the posterior choroidal artery territory, and 2 in the medial striate artery territory. Patients of poor outcome had capsular genu infarction. It was concluded that multiplicity and multiplication of cerebral infarction were markers of the severity of the meningitis.
在43例成年脑膜炎患者中,8例(18.6%)在临床病程中发生了与脑膜炎相关的脑梗死。脑梗死总数为18个。4例预后良好的患者(3例可独立行走,1例需轮椅辅助),平均年龄39岁,每位患者脑梗死数量为1个,且未增加。4例预后不良的患者(2例呈植物状态,2例死亡),平均年龄68岁,2例患者脑梗死数量为1个,2例为2个,且其中3例随后脑梗死数量增加。脑梗死部位:纹状体内囊病变3个,内囊后肢1个,大脑中动脉供血区1个,丘脑结节动脉供血区5个,内囊膝部5个,脉络膜后动脉供血区1个,内侧纹状动脉供血区2个。预后不良的患者存在内囊膝部梗死。研究得出结论,脑梗死的多发性和增多是脑膜炎严重程度的标志。