Barry M J, Fowler F J, Bin L, Pitts J C, Harris C J, Mulley A G
Medical Practices Evaluation Center, Massachusetts General Hospital, Boston, USA.
J Urol. 1997 Jan;157(1):10-4; discussion 14-5.
We defined outcomes for men with a clinical diagnosis of benign prostatic hyperplasia.
We followed for 4 years 500 candidates for elective prostatectomy treated nonoperatively in 5 North American urology practices.
There were 371 survivors with complete data at 4 years. Of 60 men with mild, 245 with moderate and 66 with severe baseline symptoms 10, 24 and 39%, respectively, had undergone surgery; 27, 31 and 27%, respectively, were on pharmacological therapy, and 63, 45 and 33%, respectively, were off active treatment at 4 years. Mild or moderate symptoms were noted at 4 years in 83, 59 and 23% of the patients, respectively, while 17, 41 and 77%, respectively, had severe symptoms or had undergone surgery.
Outcomes for men with a clinical diagnosis of benign prostatic hyperplasia depend on initial symptom severity. However, the course of symptoms also varies among patients even with the same initial symptom severity.
我们明确了临床诊断为良性前列腺增生症男性患者的预后情况。
我们对北美5家泌尿外科诊所接受非手术治疗的500例择期前列腺切除术候选患者进行了4年的随访。
4年后有371例幸存者具备完整数据。在60例轻度、245例中度和66例重度基线症状患者中，分别有10%、24%和39%接受了手术；4年后分别有27%、31%和27%接受药物治疗，分别有63%、45%和33%未接受积极治疗。4年后分别有83%、59%和23%的患者出现轻度或中度症状，而分别有17%、41%和77%的患者出现重度症状或接受了手术。
临床诊断为良性前列腺增生症男性患者的预后取决于初始症状严重程度。然而，即使初始症状严重程度相同，患者的症状发展过程也存在差异。
