一名患有巨大纵隔淋巴瘤的患者化疗后发生自发性气胸：一种罕见的肿瘤急症。

Chemotherapy-induced spontaneous pneumothorax in a patient with bulky mediastinal lymphoma: a rare oncologic emergency.

作者信息

Stein M E, Shklar Z, Drumea K, Goralnik L, Ben-Arieh Y, Haim N

机构信息

Department of Oncology, Chemotherapy Unit, Rambam Medical Center and Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.

出版信息

Oncology. 1997 Jan-Feb;54(1):15-8. doi: 10.1159/000227654.

DOI:10.1159/000227654

PMID:8978586

Abstract

Chemotherapy-induced spontaneous pneumothorax (SP) has been described sporadically in chemosensitive tumors, particularly sarcoma, with multiple lung metastases. We present a patient who developed SP following rapid regression of bulky mediastinal lymphoma. Immediately on chest tube insertion, the lung recovered and further chemotherapy could be delivered uneventfully. We suggest that (1) chemotherapy-induced SP should be included amongst oncologic emergencies and that (2) a high degree of awareness of this complication is required.

摘要

化疗引起的自发性气胸（SP）在化疗敏感肿瘤，尤其是伴有多处肺转移的肉瘤中已有零星报道。我们报告一名患者，其在巨大纵隔淋巴瘤迅速消退后发生了SP。在插入胸管后，肺立即复张，后续化疗得以顺利进行。我们建议：（1）化疗引起的SP应被纳入肿瘤急症范畴；（2）需要高度警惕这一并发症。