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在帚尾袋貂(Macropus eugenii)X染色体上,核糖核苷酸还原酶(RNR)基因与甘油磷酸脱氢酶(GPD)基因紧密连锁。

Close linkage between RNR and GPD genes on the tammar wallaby (Macropus eugenii) X chromosome.

作者信息

McKenzie L M, Johnston P G, Eldridge M D, Cooper D W

机构信息

School of Biological Sciences, Macquarie University, Sydney, New South Wales, Australia.

出版信息

Cytogenet Cell Genet. 1996;72(2-3):197-9. doi: 10.1159/000134188.

Abstract

No recombination was detected between two X-linked loci, RNR (Xp) and GPD (Xq), among 69 backcross progeny of two distantly related tammar wallaby (Macropus eugenii) subspecies. RNR loci are not dosage compensated, whereas the GPD locus is subject to the paternal X chromosome inactivation system that characterises female marsupials. The border of the region controlled by the marsupial X chromosome inactivation system has therefore been shown to lie between RNR and GPD.

摘要

在两个远缘的帚尾袋貂(Macropus eugenii)亚种的69个回交后代中,未检测到两个X连锁基因座RNR(Xp)和GPD(Xq)之间发生重组。RNR基因座不存在剂量补偿,而GPD基因座则受父本X染色体失活系统控制,该系统是雌性有袋类动物的特征。因此,有袋类动物X染色体失活系统所控制区域的边界已被证明位于RNR和GPD之间。

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