利用荧光原位杂交分析将人类GATA4基因定位于8p23.1→p22。
Assignment of the human GATA4 gene to 8p23.1-->p22 using fluorescence in situ hybridization analysis.
作者信息
Huang W Y, Heng H H, Liew C C
机构信息
Department of Clinical Biochemistry, Toronto Hospital, University of Toronto, Ont., Canada.
出版信息
Cytogenet Cell Genet. 1996;72(2-3):217-8. doi: 10.1159/000134194.
PMID:8978781
Abstract
Using fluorescence in situ hybridization, the human GATA4 gene, a member of the zinc-finger protein family recognizing the consensus GATA motif, was mapped to 8p23.1-->p22. This result, in conjunction with gene mapping data on other GATA-DNA binding proteins, suggests that genes encoding GATA-DNA binding proteins are dispersed throughout the genome, rather than clustered within a single locus.
摘要
利用荧光原位杂交技术，人类GATA4基因（一种识别共有GATA基序的锌指蛋白家族成员）被定位到8p23.1→p22。这一结果，结合其他GATA-DNA结合蛋白的基因定位数据，表明编码GATA-DNA结合蛋白的基因分散于整个基因组中，而非聚集在单个位点。
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