[阿霉素的特性及有效用法]
[Characteristic and effective usage of adriamycin].
作者信息
Horiuchi K, Akimoto M
机构信息
Dept. of Urology, Nippon Medical School.
出版信息
Gan To Kagaku Ryoho. 1996 Dec;23(14):1916-9.
The utility of adriamycin (doxorubicin), an anti-cancer antibiotic, for the treatment of transitional cell carcinoma of the bladder has been appreciated. Adriamycin is still used intravesically for superficial bladder cancer to avoid implantation of floating cancer cells after transurethral resection, to decrease the incidence of recurrence and treat an unresected part of the tumor. On the other hand, cisplatin-based multi-drug chemotherapies including adriamycin have proven effective in treating locally and systemically advanced bladder cancer.
阿霉素（多柔比星）作为一种抗癌抗生素，其在治疗膀胱移行细胞癌方面的效用已得到认可。阿霉素仍被用于膀胱内灌注治疗浅表性膀胱癌，以避免经尿道切除术后漂浮癌细胞的种植，降低复发率并治疗肿瘤未切除部分。另一方面，包括阿霉素在内的基于顺铂的多药化疗已被证明在治疗局部和全身晚期膀胱癌方面有效。
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