Kumari P K, Chellam V G, Madhavan J, Ratheesan K, Pillai G R, Kumar S R, Nair M K
Department of Pediatric Oncology, Regional Cancer Center, Trivandrum.
Indian Pediatr. 1996 Jul;33(7):561-5.
To assess the efficacy of primary chemotherapy in patients with clinically staged Hodgkin's disease.
Non randomized study.
Pediatric Oncology Division of Regional Cancer Center.
Twenty nine children with Hodgkin's disease.
Chemotherapy was given to 21 patients whose parents agreed for the same. Sixteen children received COPP regimen and 5 received MOPP regimen.
Complete remission was achieved in 19 patients. The relapse free survival and overall survival in these patients were 76% and 86%, respectively at 5 years. There was no death related to chemotherapy toxicity.
Combination chemotherapy is an effective modality of treatment for children with Hodgkin's disease.
评估临床分期霍奇金病患者的一线化疗疗效。
非随机研究。
地区癌症中心儿科肿瘤学部。
29例霍奇金病患儿。
21例患儿家长同意后接受化疗。16例患儿接受COPP方案，5例接受MOPP方案。
19例患者实现完全缓解。这些患者的5年无复发生存率和总生存率分别为76%和86%。无化疗毒性相关死亡。
联合化疗是治疗儿童霍奇金病的有效方式。
