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可卡因包裹摄入的保守治疗:在意大利主要的南美可卡因走私中心米兰的经验。

Conservative management of cocaine-packet ingestion: experience in Milan, the main Italian smuggling center of South American cocaine.

作者信息

Aldrighetti L, Paganelli M, Giacomelli M, Villa G, Ferla G

机构信息

IRCCS H San Raffaele, Milan, Italy.

出版信息

Panminerva Med. 1996 Jun;38(2):111-6.

PMID:8979743
Abstract

OBJECTIVE

To assess retrospectively the effectiveness and the safety of the conservative medical management of asymptomatic cocaine body-packers.

DESIGN

Case series collected during twelve years (1980-1992).

SETTING

Milan Airports Health Center. Department of Surgery and Intensive Care Unit of San Raffaele Hospital-University of Milan.

PARTICIPANTS

189 suspected cocaine body packers (143 male, 53 female), aged between 18-53 years, were brought to our observation by customs after disembarking at the Milan International Airports of Malpensa and Linate. 61 subjects (32%) turned to be carriers of packets containing cocaine (ovules).

INTERVENTIONS

Medical conservative treatment, based on close clinical observation and light solid diet, free assumption of liquids and oily laxatives. Plain abdominal X-ray and ultrasound were performed for the diagnosis of cocaine packet ingestion and then repeated up to the complete evacuation of all ovules. Two laparotomies with surgical removal of ovules in symptomatic patients (bowel obstruction and acute cocaine intoxication due to the intraluminal rupture).

MEASURES

Physical examination with neurological assessment every 8 hours and vital signs (including blood pressure, heart frequency and temperature) every 4 hours to detect complications (acute cocaine intoxication, bowel obstruction or perforation) secondary to cocaine packet ingestion. Structural features of the containers, cocaine amount per ovule, and rate and indications for surgical treatment have been reviewed.

RESULTS

Evacuation period lasted from 3 to 6 days. Ingested containers varied from 52 to 117 with a mean of 88 +/- 13 ovules for each body packer. Total amount of recovered 95% pure cocaine hydrochloride was 41 kilograms. Signs of cocaine toxicity and bowel obstruction requiring emergency laparotomy occurred in two cases (3.3%). Both patients recovered uneventfully.

CONCLUSIONS

Conservative management during spontaneous evacuation of the containers is the first choice approach to the body-packet ingestion. Close clinical observation allows an early detection of the patients with complications requiring emergency surgical treatment.

摘要

目的

回顾性评估无症状可卡因体内携带包装者保守药物治疗的有效性和安全性。

设计

收集了十二年(1980 - 1992年)间的病例系列。

地点

米兰机场健康中心。米兰大学圣拉斐尔医院外科及重症监护病房。

参与者

189名疑似可卡因体内携带包装者(143名男性,53名女性),年龄在18至53岁之间,在马尔彭萨和利纳特米兰国际机场下机后被海关带到我们这里接受观察。61名受试者(32%)被证实为装有可卡因(药粒)包裹的携带者。

干预措施

基于密切临床观察和清淡固体饮食、自由饮用液体及油性泻药的药物保守治疗。进行腹部平片和超声检查以诊断可卡因包裹摄入情况,之后反复检查直至所有药粒完全排出。对出现症状的患者(肠梗阻及因肠腔内破裂导致的急性可卡因中毒)进行了两次剖腹手术以手术取出药粒。

测量指标

每8小时进行一次包括神经学评估的体格检查,每4小时测量生命体征(包括血压、心率和体温)以检测因可卡因包裹摄入继发的并发症(急性可卡因中毒、肠梗阻或穿孔)。对容器的结构特征、每个药粒中的可卡因含量、手术治疗的发生率及指征进行了评估。

结果

排出期持续3至6天。摄入的容器数量从52个到117个不等,每个体内携带包装者平均有88 ± 13个药粒。回收的95%纯盐酸可卡因总量为41千克。有两例(3.3%)出现了需要紧急剖腹手术的可卡因中毒迹象和肠梗阻。两名患者均顺利康复。

结论

在容器自然排出期间进行保守治疗是处理体内携带包装可卡因摄入的首选方法。密切的临床观察能够早期发现需要紧急手术治疗的并发症患者。

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