Gast R K, Benson S T
United States Department of Agriculture, Agricultural Research Service, Southeast Poultry Research Laboratory, Athens, Georgia 30605, USA.
Avian Dis. 1996 Oct-Dec;40(4):853-7.
Phage type 4 Salmonella enteritidis strains have only recently been isolated from poultry and humans in the United States, although this phage type predominates in many other countries. The present study assessed the ability of S. enteritidis isolates of various phage types found in the United States (including phage type 4) to colonize the intestinal tract and invade to reach internal organs in experimentally infected chicks. Groups of 5-day-old single-comb white leghorn chicks were inoculated with a range of oral doses of three phage type 4 isolates and three isolates of other phage types. Although some significant differences were observed between individual S. enteritidis isolates in the frequencies at which they colonized the intestinal tracts and invaded to reach the spleens of inoculated chicks, no consistent overall pattern differentiated phage type 4 isolates from isolates of other phage types.
4型噬菌体肠炎沙门氏菌菌株最近才在美国的家禽和人类中分离出来，尽管这种噬菌体类型在许多其他国家占主导地位。本研究评估了在美国发现的各种噬菌体类型（包括4型噬菌体）的肠炎沙门氏菌分离株在实验感染雏鸡中定殖于肠道并侵入到内部器官的能力。将5日龄单冠白来航雏鸡分成若干组，分别口服一系列剂量的三种4型噬菌体分离株和三种其他噬菌体类型的分离株。尽管在个别肠炎沙门氏菌分离株定殖于肠道并侵入接种雏鸡脾脏的频率上观察到一些显著差异，但没有一致的总体模式能够区分4型噬菌体分离株和其他噬菌体类型的分离株。
