Uchihara T, Inaba A, Yokota T, Furukawa T
Department of Neurology, Faculty of Medicine, Tokyo Medical and Dental University, Japan.
J Neurol Sci. 1996 Nov;143(1-2):173-5. doi: 10.1016/s0022-510x(96)00193-1.
Progressive clumsiness developed in the right hand of a 33-year-old man, became bilateral and evolved very slowly for ten years. Another neurological deficit was restricted to a slight impairment of superficial sensations. Magnetic resonance imaging verified an atrophy of bilateral parietal lobes. The cerebral blood flow was markedly decreased in the atrophic area. Pure clumsiness of a very slowly progressive course due to parietal atrophy has never been reported in such a young adult. This clinical picture may suggest another variety of degenerative process.
一名33岁男性右手出现进行性笨拙,随后发展为双侧性,且在十年间进展非常缓慢。另一个神经功能缺损仅限于轻度的浅感觉障碍。磁共振成像证实双侧顶叶萎缩。萎缩区域的脑血流量明显减少。在如此年轻的成年人中,从未有过因顶叶萎缩导致的进展非常缓慢的单纯性笨拙的报道。这种临床表现可能提示另一种退行性病变。