Moreira M A, Almeida C A, Canavez F, Olicio R, Seuánez H N
Genetics Section, Instituto Nacional de Câncer, Praça da Cruz Vemelha, Rio de Janeiro, Brazil.
J Hered. 1996 Nov-Dec;87(6):456-60. doi: 10.1093/oxfordjournals.jhered.a023037.
Heteroduplex mobility assays (HMAs) of a cytochrome b region were used for estimating genetic distances and phylogenetic relationships between some selected neotropical primates of the families Callitrichidae (marmosets and tamarins) and Cebidae [capuchin monkey, (Cebus apella)], and man (Homo sapiens). HMA distances were found to be strongly correlated to analogous estimates derived from DNA sequence data. Phylogenetic trees obtained by HMAs and sequence analyses showed similar topologies with almost identical intraspecific, intrageneric, and intergeneric relationships. The applicability of HMAs is assessed relative to different levels of molecular and organismal diversity.
利用细胞色素b区域的异源双链迁移率分析(HMA)来估计绢毛猴科(狨猴和柽柳猴)和卷尾猴科(卷尾猴,Cebus apella)的一些新热带灵长类动物与人类(智人)之间的遗传距离和系统发育关系。发现HMA距离与从DNA序列数据得出的类似估计值高度相关。通过HMA和序列分析获得的系统发育树显示出相似的拓扑结构,具有几乎相同的种内、属内和属间关系。相对于不同水平的分子和生物多样性评估了HMA的适用性。