Nikander P, Boguslawsky P v
TIT J Life Sci. 1977;7(1-2):1-6.
The sodium and potassium contents in cerebral cortex slices incubated in bicarbonate medium from alcohol preferring (AA) and alcohol avoiding (ANA) rats were measured during electrical stimulation and subsequent recovery. The intracellular quantities were estimated on the basis of the inulin distribution. The amount of intracellular potassium in unstimulated slices from the two strains was different, the AA rats showing a higher level. No differences in the entry of sodium were observed for the two strains when slices incubated with ethanol were subjected to electrical stimulation, but the loss of potassium was 46% greater in the AA rats. During recovery no ethanol-induced inhibition of theloss of sodium ions was seen in either strain, whereas the gain of potassium ions was inhibited in the ANA rats and not in the AA RATS. The potassium gain in the presence of ethanol was 42% greater during the recovery period in the AA rats.
在电刺激及随后的恢复过程中，对来自嗜酒（AA）和厌酒（ANA）大鼠的大脑皮质切片在碳酸氢盐培养基中孵育时的钠和钾含量进行了测量。根据菊粉分布估算细胞内含量。两种品系未受刺激切片中的细胞内钾含量不同，AA大鼠的含量较高。当用乙醇孵育的切片受到电刺激时，两种品系的钠进入量未观察到差异，但AA大鼠的钾流失量要大46%。在恢复过程中，两个品系均未观察到乙醇诱导的钠离子流失抑制现象，而ANA大鼠的钾离子增加受到抑制，AA大鼠则未受抑制。在恢复期间，AA大鼠在有乙醇存在的情况下钾增加量要大42%。
