Delgado E
Crit Care Nurs Q. 1996 Nov;19(3):23-35. doi: 10.1097/00002727-199619030-00003.
One of the many challenges in the management of the patient with adult respiratory distress syndrome is optimal application of mechanical ventilation. Pressure controlled-inverse ratio ventilation has surfaced as a possible alternative to conventional ventilation for patients affected by this condition. In pressure controlled-inverse ratio ventilation, the conventional inspiratory-to-expiratory ratio is reversed, allowing the inspiratory phase to lengthen with an accompanying increase in mean airway pressure. When carefully applied, mean airway pressure adjustments can be manipulated without increases in positive end-expiratory pressure and peak airway pressure, thus minimizing the risk of alveolar rupture and worsening of lung injury.
成人呼吸窘迫综合征患者管理中众多挑战之一是机械通气的优化应用。压力控制反比通气已成为治疗这种疾病患者的传统通气的一种可能替代方法。在压力控制反比通气中，传统的吸气与呼气比率被颠倒，使吸气阶段延长，同时平均气道压力增加。谨慎应用时，可在不增加呼气末正压和气道峰值压力的情况下调节平均气道压力，从而将肺泡破裂和肺损伤恶化的风险降至最低。
