Sato K, Takahashi T, Ashikaga K, Hanyu N, Aoki T
Dept. of Surgery, Fuji Municipal Hospital.
Gan To Kagaku Ryoho. 1996 Dec;23 Suppl 3:252-5.
The clinical response and QOL were examined with 16 outpatients treated with home hepatic arterial infusion chemotherapy for liver metastasis from colorectal cancer. Fluorouracil 1,000 mg/body/week was administered by 5-hour intra-arterial infusion with a portable disposable pump. Six out of 8 who replied to a questionnaire survey led a their usual life during the treatment, and the average hospitalization period was only 7 days (including mortal cases). The clinical response was evaluated with 13 patients; 3 prophylactic treatment cases were excluded from the original 16 cases. The number of partial responses and no change were 3 and 7, respectively, and the overall response rate was 23.1%. These studies suggest that home hepatic arterial infusion chemotherapy is beneficial for patients with liver metastasis by improving their QOL.
对16例接受家庭肝动脉灌注化疗治疗结直肠癌肝转移的门诊患者的临床反应和生活质量进行了研究。使用便携式一次性泵通过5小时动脉内输注给予氟尿嘧啶1000mg/人/周。在回复问卷调查的8人中，有6人在治疗期间过着正常生活，平均住院时间仅为7天（包括死亡病例）。对13例患者进行了临床反应评估；最初的16例中排除了3例预防性治疗病例。部分缓解和病情稳定的病例数分别为3例和7例，总缓解率为23.1%。这些研究表明，家庭肝动脉灌注化疗通过改善生活质量对肝转移患者有益。
