Scanni A, Licciardello L, Trovato M, Tomirotti M, Biraghi M
Tumori. 1977 Mar-Apr;63(2):175-80. doi: 10.1177/030089167706300208.
Serum copper and ceruloplasmin levels were determined in patients with solid neoplasias in different sites (stomach, large intestine, lung). Statistical analysis showed that serum copper levels increased significantly in all the forms studied. The serum ceruloplasmin level, on the contrary, was high in gastric and pulmonary cancer, while in tumors localised in the large intestine the increase was not significant. In 58 cases, there was a correlation between copper and ceruloplasmin levels in the same subject; this correlation proved significant solely in gastric forms. Moreover, statistical analysis of the two parameters in question did not reveal any significant differences between localized and metastasized in forms.
测定了不同部位（胃、大肠、肺）实体瘤患者的血清铜和铜蓝蛋白水平。统计分析表明，在所研究的所有类型中血清铜水平均显著升高。相反，血清铜蓝蛋白水平在胃癌和肺癌中较高，而在大肠肿瘤中升高不显著。在58例病例中，同一受试者的铜和铜蓝蛋白水平之间存在相关性；这种相关性仅在胃癌类型中显著。此外，对上述两个参数的统计分析未发现局部型和转移型之间有任何显著差异。
