Kharlanova N G, Lomov Iu M, Tkacheva T I, Bardakhch'ian E A
Morfologiia. 1996;109(3):67-71.
A culture of virulent selection of cholera vibrios L-top 5879 was introduced through the probe to suckling rabbits-pups 10 to 12 days old. Ultrastructural changes of interstitial cells and capillaries of kidney medulla were studied. During vibrio adhesion (4 hrs after the inaction) interstitial cells acquire dystrophic changes, lipid granules content reduces, while vascular permeability grows higher which suggests the presence of prostaglandin precursors elimination into blood flow. Cholera development (1-2 days later) is accompanied with progressing of signs of prostaglandin synthesis activation and their precursors passage into the vascular bed.
通过探针将霍乱弧菌L-top 5879的强毒选择培养物接种到10至12日龄的哺乳兔仔体内。研究了肾髓质间质细胞和毛细血管的超微结构变化。在弧菌黏附期间（接种后4小时），间质细胞出现营养不良性变化，脂质颗粒含量减少，而血管通透性增加，这表明前列腺素前体进入血流。霍乱发展（1 - 2天后）伴随着前列腺素合成激活迹象的进展及其前体进入血管床。
