Shved M I, Palamar T O
Lik Sprava. 1995 Sep-Dec(9-12):72-5.
A total of 78 female patients of child-bearing age with iron deficiency anemia (IDA) of varying genesis and degree of severity were examined for effectiveness of a synthetic antioxidant emoxypine in a combined treatment of IDA. IDA was found to be associated with activation of lipid peroxidation processes (LPO) and decrement in antioxidant defence of the body. Conventional antianemic therapy does not lead to normalization of parameters characterizing LPO. Incorporation into a complex therapy of a synthetic antioxidant emoxypine reduces activity of free-radical oxidation of lipids, which fact prevents the pathological process from progressing and leads to more rapid and lasting clinical remission.
共对78名不同病因和严重程度的缺铁性贫血（IDA）育龄女性患者进行了研究，以探讨合成抗氧化剂依莫昔平在IDA联合治疗中的有效性。研究发现，IDA与脂质过氧化过程（LPO）的激活及机体抗氧化防御能力的下降有关。传统抗贫血疗法无法使表征LPO的参数恢复正常。在综合治疗中加入合成抗氧化剂依莫昔平可降低脂质自由基氧化活性，这一事实可防止病理过程进展，并导致更快速、持久的临床缓解。
