Christens-Barry W A, Green W J, Connolly P J, Farrell R A, McCally R L
Johns Hopkins University Applied Physics Laboratory, Laurel, MD 20723-6099, USA.
Exp Eye Res. 1996 Jun;62(6):651-62. doi: 10.1006/exer.1996.0076.
In this paper polarized light transmission measurements are made under conditions that closely approximate the physiological state in order to probe lamellar structure in the central cornea of New Zealand white rabbits. The results are interpreted with the aid of a newly developed theory (published elsewhere) in which the cornea is modeled as stacked birefringent layers corresponding to the lamellae. The theory enables predictions of the statistical properties of lamellar ordering based on characteristics of the transmission of polarized light. The experimental results are consistent with a structure in which a number of lamellae have a fixed azimuthal orientation (i.e. about an axis normal to the corneal surface), whereas the remainder are essentially randomly oriented. Comparisons with the theoretical predictions are consistent with a model in which the preferred direction in the apical region of the cornea does not vary significantly among rabbits; and the preferred lamellar orientation direction determined for the population measured here is very close to that suggested in previous experiments on a smaller number of rabbits. Mapping experiments using a new goniometric holder showed that the preferential order at the apical region is closely preserved throughout the central approximately 4 mm diameter optical zone in individual corneas.
在本文中，为了探究新西兰白兔中央角膜的板层结构，在与生理状态非常接近的条件下进行了偏振光透射测量。借助一种新开发的理论（已在其他地方发表）对结果进行了解释，该理论将角膜建模为与板层相对应的堆叠双折射层。该理论能够根据偏振光透射特性预测板层排列的统计特性。实验结果与这样一种结构一致：其中一些板层具有固定的方位取向（即围绕垂直于角膜表面的轴），而其余板层基本上是随机取向的。与理论预测的比较与以下模型一致：在该模型中，角膜顶端区域的优选方向在兔子之间没有显著变化；并且在此处测量的群体中确定的优选板层取向方向与先前在较少数量兔子上进行的实验中所建议的方向非常接近。使用新型测角支架进行的映射实验表明，在单个角膜中，中央直径约4毫米的光学区域内，顶端区域的优先排列在整个区域内都得到了紧密保留。
