Michel C C
Department of Physiology and Biophysics, Imperial College School of Medicine at St Mary's.
J Mal Vasc. 1996;21 Suppl C:239-44.
To review the mechanisms of oxygen transport in the walls of arteries and veins and to consider whether oxygen transport might limit oxygen consumption in the venous wall.
(i) To review evidence for the contributions of transport from the vascular lumen and transport from the vasa vasorum to the supply of oxygen to the walls of arteries. (ii) To use the general principles of oxygen diffusion through tissues to extrapolate the findings of investigations of oxygen transport into arterial walls to transport into the walls of the larger veins.
The magnitude of oxygen transport from the vessel lumen into the vessel wall is dependent on the partial pressure of oxygen (PO2) in the vessel lumen. While luminal PO2 is constant and high in arteries, it is a physiological variable in veins of healthy people. In larger veins, there is evidence that flow in the vasa vasorum increases as PO2 in the vessel lumen falls. The extent to which this regulatory action of the vasa vasorum may be comprised by raised venous pressure and venous distension has not been defined.
回顾动脉壁和静脉壁中氧运输的机制，并探讨氧运输是否可能限制静脉壁中的氧消耗。
(i) 回顾来自血管腔的运输以及来自血管滋养管的运输对动脉壁氧供应贡献的证据。(ii) 运用氧在组织中扩散的一般原理，将动脉壁氧运输的研究结果外推至较大静脉壁的氧运输。
从血管腔到血管壁的氧运输量取决于血管腔内的氧分压（PO2）。在动脉中，管腔内的PO2恒定且较高，而在健康人的静脉中，它是一个生理变量。在较大静脉中，有证据表明随着血管腔内PO2的下降，血管滋养管中的血流增加。血管滋养管的这种调节作用在多大程度上可能会受到静脉压升高和静脉扩张的影响尚未明确。
