Belcaro G, Laurora G, Cesarone M R, De Sanctis M T, Incandela L, Taccoen A, Nicolaides A N
Microcirculation Laboratory, Chieti University, Pierangeli Clinic, Pescara, Italie.
J Mal Vasc. 1996;21 Suppl C:253-8.
Venous wall flux was measured using laser-Doppler flowmetry on the external surface of 24 normal veins, partially dissected during the preparation of the vein for aortocoronary bypass grafting. Measurements were performed before the final dissection of the vein when at least 3/4 of the adventitia and periadventitia tissue was still intact for a length of 3 cm. The segment of vein (10 cm) proximal to the sapheno-femoral junction was studied. Measurements were repeated on 22 varicose veins before stripping or ligation of the sapheno-femoral junction. Flux was measured with a Laserflo (Vasamedics) flowmeter. A Delrin (polycarbonate) spacer was placed between the probe and the vein wall surface. Measurements shown are the average of three minutes recording. Preliminary analysis indicates that flux appears to be lower in varicose veins in comparison with flux in the normal vein wall. However the variability of results and technical problems in flux measurements indicate the need of a larger measurement sample before confirming the observation of a decreased perfusion of the varicose venous wall.
使用激光多普勒血流仪在24条正常静脉的外表面测量静脉壁血流量，这些静脉是在准备用于主动脉冠状动脉搭桥术的静脉时部分解剖的。在静脉最终解剖前进行测量，此时至少3/4的外膜和外膜周围组织在3厘米长度内仍保持完整。研究了大隐静脉-股静脉交界处近端10厘米的静脉段。在大隐静脉-股静脉交界处剥脱或结扎前，对22条曲张静脉重复进行测量。使用Laserflo（Vasamedics）流量计测量血流量。在探头与静脉壁表面之间放置一个聚碳酸酯间隔物。所示测量值为三分钟记录的平均值。初步分析表明，与正常静脉壁的血流量相比，曲张静脉中的血流量似乎较低。然而，结果的变异性和血流量测量中的技术问题表明，在确认观察到曲张静脉壁灌注减少之前，需要更大的测量样本。
