Clemmesen J O, Ott P, Dalhoff K P, Astrup L B, Tage-Jensen U, Poulsen H E
Medicinsk afdeling A-2101, Rigshospitalet, København.
Ugeskr Laeger. 1996 Nov 25;158(48):6892-5.
Based on recent reports concerning the efficacy of N-acetylcysteine (NAC) in paracetamol (acetaminophen) poisoning, guidelines for treatment and control of these patients are reviewed by a study group under the Danish Association for the Study of the Liver. It is recommended that NAC-treatment is initiated immediately after referral and continued for 36 hours in all cases. Further NAC-treatment should not be discontinued before a decrease in INR has been observed.
基于近期有关N-乙酰半胱氨酸(NAC)对扑热息痛(对乙酰氨基酚)中毒疗效的报告,丹麦肝脏研究协会下属的一个研究小组对这些患者的治疗和控制指南进行了审查。建议在转诊后立即开始NAC治疗,并在所有病例中持续36小时。在观察到国际标准化比值(INR)下降之前,不应停止进一步的NAC治疗。