Sterzl I, Zamrazil V
Endokrinologický ústav, Praha.
Vnitr Lek. 1996 Sep;42(9):624-6.
Fatigue is a frequent and sometimes dominant symptom of some endocrinopathies. It may be associated with other symptoms which are included among the criteria of the chronic fatigue syndrome. These units are not always quite distinct and frequently endocrine diseases and chronic fatigue syndrome (CFS) overlap. From this ensue differential diagnostic problems and ideas on possible causal relations. The authors concentrate in articular on autoimmune endocrinopathies and the polyglandular autoimmune syndrome (APS) with emphasis on the necessity of an accurate endocrinological diagnosis, where is some patients with suspected CFS a defined endocrinopathy was revealed. Attention will be also paid to recent views on the possible participation of disorders of the hypothalamus-pituitary-adrenal axis in the etiopathogenesis of CFS where endocrine and immune regulation overlap and condition each other.
疲劳是某些内分泌疾病常见且有时占主导的症状。它可能与其他症状相关，这些症状包含在慢性疲劳综合征的标准之中。这些症状并不总是完全不同，内分泌疾病和慢性疲劳综合征（CFS）常常相互重叠。由此产生了鉴别诊断问题以及关于可能因果关系的观点。作者特别关注自身免疫性内分泌疾病和多腺体自身免疫综合征（APS），强调准确的内分泌诊断的必要性，因为在一些疑似CFS的患者中发现了明确的内分泌疾病。还将关注下丘脑 - 垂体 - 肾上腺轴紊乱可能参与CFS发病机制的最新观点，其中内分泌和免疫调节相互重叠并相互影响。
