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Regulation of cell cycle synchronization by decapentaplegic during Drosophila eye development.

作者信息

Penton A, Selleck S B, Hoffmann F M

机构信息

McArdle Laboratory for Cancer Research and Laboratory of Genetics, University of Wisconsin Medical School, Madison, WI 53706, USA.

出版信息

Science. 1997 Jan 10;275(5297):203-6. doi: 10.1126/science.275.5297.203.

DOI:10.1126/science.275.5297.203
PMID:8985012
Abstract

In the developing Drosophila eye, differentiation is coordinated with synchronized progression through the cell cycle. Signaling mediated by the transforming growth factor-beta-related gene decapentaplegic (dpp) was required for the synchronization of the cell cycle but not for cell fate specification. DPP may affect cell cycle synchronization by promoting cell cycle progression through the G2-M phases. This synchronization is critical for the precise assembly of the eye.

摘要

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