Complete synthesis of 3'-sialyl-N-acetyllactosamine by regioselective transglycosylation.
作者信息
Vetere A, Paoletti S
机构信息
Dipartimento di Biochimica, Biofisica e Chimica delle Macromolecole, Università degli Studi di Trieste, Italy.
出版信息
FEBS Lett. 1996 Dec 16;399(3):203-6. doi: 10.1016/s0014-5793(96)01267-7.
PMID:8985145
Abstract
Transglycolytic synthesis of 3'-sialyl-N-acetyllactosamine by sequential use of beta-galactosidase from Bacillus circulans and trans-sialidase from Trypanosoma cruzi was described. These reactions depicted the first complete synthesis of a biologically important oligosaccharide with high regioselectivity avoiding use of glycosyltransferases and NDP sugars.
摘要
Zotero 插件