Winchester K, Mathers W D, Sutphin J E
University of Iowa Hospitals and Clinics, Department of Ophthalmology, Iowa City, USA.
Cornea. 1997 Jan;16(1):27-31.
Confocal microscopy provides a new, noninvasive way of imaging the human cornea in vivo. One of its most important clinical uses is the diagnosis and management of infectious keratitis. The authors used tandem scanning confocal microscopy to image the corneas in two culture-proven cases of Aspergillus keratitis. Fungal hyphae were imaged as high-contrast filaments 6 microns in diameter from 60 to 400 microns in length. Confocal microscopy may be a fast and safe diagnostic tool in determining the presence of fungal hyphae in vivo within the human cornea.
共聚焦显微镜检查为在体成像人角膜提供了一种新的、非侵入性方法。其最重要的临床用途之一是感染性角膜炎的诊断和处理。作者使用串联扫描共聚焦显微镜对两例经培养证实的曲霉菌性角膜炎患者的角膜进行成像。真菌菌丝被成像为直径6微米、长度60至400微米的高对比度细丝。共聚焦显微镜检查可能是一种快速且安全的诊断工具，用于确定人角膜内活体真菌菌丝的存在。
