Svensson E, Starmark J E, Ekholm S, von Essen C, Johansson A
Department of Mathematics, Chalmers University of Technology, Sweden.
Neurol Res. 1996 Dec;18(6):487-94. doi: 10.1080/01616412.1996.11740459.
The purpose of this study was to analyse factors for interobserver disagreements in two scales used for the assessments of the amount of blood in subarachnoid space (Fisher grading) and of acute hydrocephalus on computerized tomographic (CT) scans. The assessments made by four neuroradiologists on 59 CT scans obtained in the acute stage after subarachnoid hemorrhage were analysed by a statistical method by Svensson and Holm. This method permits the separation of the inter-observer disagreements in their random and systematic components. The overall consistency of the assessments was significant (p < 0.0005) but the neuroradiologists disagreed on half of the CT-scans. The kappa values were 0.50-0.63. The analysis showed that the main reason for disagreements was systematic inter-observer differences in their use of the clinically most important parts of staging, i.e. subarachnoid clot or intraventricular blood (Fisher grading) and too low categories (hydrocephalus). The main conclusion from this study is that the proper remedy for Fisher grading and for grading of hydrocephalus is a sharpening of the criteria of specific category levels and given this improvement both grading systems will show a high level of reliability.
本研究的目的是分析在用于评估蛛网膜下腔出血量(Fisher分级)和计算机断层扫描(CT)上急性脑积水的两种量表中,观察者间存在分歧的因素。Svensson和Holm采用统计学方法分析了四位神经放射科医生对蛛网膜下腔出血急性期获得的59份CT扫描的评估结果。该方法能够将观察者间分歧的随机成分和系统成分区分开来。评估的总体一致性具有显著性(p < 0.0005),但神经放射科医生在一半的CT扫描上存在分歧。kappa值为0.50 - 0.63。分析表明,分歧的主要原因是观察者在使用分期中临床上最重要的部分(即蛛网膜下腔血凝块或脑室内血液(Fisher分级))以及分类过低(脑积水)方面存在系统性的观察者间差异。本研究的主要结论是,对Fisher分级和脑积水分级的适当补救措施是细化特定类别水平的标准,鉴于这一改进,两种分级系统都将显示出高度的可靠性。