Ebskov L B
Department of Orthopaedic Surgery, Herlev Hospital, University of Copenhagen, Denmark.
Prosthet Orthot Int. 1996 Dec;20(3):147-52. doi: 10.3109/03093649609164436.
A nationwide epidemiological study included 3516 primary major lower limb amputations in diabetic patients, during the period 1982 to 1992. On this well defined diabetic amputee population the relative mortality (Standard Mortality Ratio, SMR) has been analysed. The mortality rate was found to be 8 times the expected during the first year following amputation. The relative mortality is higher for females than males. An inverse relation between age and SMR was found, and the SMR was significantly related to the level of amputation. No significant difference could be detected when analysing SMR in relation to subdiagnosis (NIDDM vs IDDM) or SMR in relation to the period of treatment 1982-87 versus 1988-92.
一项全国性的流行病学研究涵盖了1982年至1992年期间糖尿病患者的3516例主要下肢初次截肢病例。针对这一定义明确的糖尿病截肢患者群体，分析了相对死亡率（标准化死亡率，SMR）。发现截肢后第一年的死亡率是预期的8倍。女性的相对死亡率高于男性。发现年龄与SMR呈负相关，且SMR与截肢水平显著相关。在分析与亚诊断（非胰岛素依赖型糖尿病与胰岛素依赖型糖尿病）相关的SMR或与1982 - 1987年与1988 - 1992年治疗期间相关的SMR时，未检测到显著差异。
