Zaphiris H A, Blaisdell G D, Jermain D M
Department of Psychiatry and Behavioral Sciences, Texas A&M University College of Medicine, Scott & White Hospital and Clinic, Temple 76508, USA.
Ann Clin Psychiatry. 1996 Dec;8(4):207-10. doi: 10.3109/10401239609147762.
Nefazodone is a new antidepressant exhibiting properties of selective serotonin reuptake inhibition and serotonin-2 receptor antagonism. There has been only one other published case of induction of mania in a patient treated with nefazodone. This report describes a second case of probable induction of mania with nefazodone therapy and briefly reviews clinical and theoretical considerations involved in this process.
奈法唑酮是一种新型抗抑郁药，具有选择性5-羟色胺再摄取抑制和5-羟色胺2受体拮抗特性。在用奈法唑酮治疗的患者中，仅有另一例关于躁狂发作诱导的病例发表。本报告描述了第二例可能由奈法唑酮治疗诱发躁狂的病例，并简要回顾了这一过程中涉及的临床和理论考量因素。
