Tziortziotis D V, Bouros A C, Ziogas V S, Young R H
Departments of Pathology, LITO Hospital, Athens, Greece.
Int J Gynecol Pathol. 1997 Jan;16(1):79-80. doi: 10.1097/00004347-199701000-00013.
A case of clear cell hyperplasia of the fallopian tube epithelium associated with ectopic pregnancy is described. The lesion was encountered in a 31-year-old woman who presented with abdominal pain and had a positive pregnancy test. Ultrasound examination disclosed an enlarged right fallopian tube. The patient underwent laparotomy, at which time the right fallopian tube was excised. On gross examination, a firm, 1.2 x 1 x 1-cm nodule almost obliterating the lumen of the tube and an abundant blood clot were present. On histologic examination, chorionic villi were found in the blood clot. The nodule was composed of epithelial cells that formed solid and glandular structures. The cells had clear cytoplasm and nuclei without atypia. The differential diagnosis included clear cell adenocarcinoma, but clear cell hyperplasia associated with pregnancy was diagnosed because of the absence of cytologic atypia and mitotic figures. The patient has had an uneventful postoperative follow-up period of 1 year.
本文描述了一例与异位妊娠相关的输卵管上皮透明细胞增生病例。该病变见于一名31岁女性，她因腹痛就诊且妊娠试验呈阳性。超声检查发现右侧输卵管增粗。患者接受了剖腹手术，术中切除了右侧输卵管。大体检查可见一个质地坚实、大小为1.2×1×1厘米的结节，几乎阻塞了输卵管管腔，并有大量血凝块。组织学检查发现血凝块中有绒毛膜绒毛。结节由形成实性和腺性结构的上皮细胞组成。细胞胞质透明，细胞核无异型性。鉴别诊断包括透明细胞腺癌，但由于缺乏细胞学异型性和有丝分裂象，诊断为与妊娠相关的透明细胞增生。患者术后随访1年，情况良好。
