红细胞在固/液界面上的黏附。
Red blood cell adhesion on a solid/liquid interface.
作者信息
Lavalle P, Stoltz J F, Senger B, Voegel J C, Schaaf P
机构信息
Institut National de la Santé et de la Recherche Médicale, Unité 424, Fédération de Recherche Odontologique, Université Louis Pasteur, Strasbourg, France.
出版信息
Proc Natl Acad Sci U S A. 1996 Dec 24;93(26):15136-40. doi: 10.1073/pnas.93.26.15136.
Red blood cells (RBCs), previously fixed with glutaraldehyde, adhere to glass slides coated with fibrinogen. The RBC deposition process on the horizontal glass surface is investigated by analyzing the relative surface covered by the RBCs, as well as the variance of this surface coverage, as a function of the concentration of particles. This study is performed by optical microscopy and image analysis. A model, derived from the classical random sequential adsorption model, has been developed to account for the experimental results. This model highlights the strong influence of the hydrodynamic interactions during the deposition process.
先前用戊二醛固定的红细胞会黏附在涂有纤维蛋白原的载玻片上。通过分析红细胞覆盖的相对表面积以及该表面积覆盖的变化情况（作为颗粒浓度的函数），来研究水平玻璃表面上红细胞的沉积过程。这项研究通过光学显微镜和图像分析来进行。已开发出一个源自经典随机顺序吸附模型的模型，以解释实验结果。该模型突出了沉积过程中流体动力相互作用的强烈影响。
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