Oku H, Sakihama T, Chinen I
Laboratory of Applied Biochemistry, Faculty of Agriculture, University of Ryukyus, Okinawa, Japan.
Biosci Biotechnol Biochem. 1996 Oct;60(10):1724-5. doi: 10.1271/bbb.60.1724.
Isoleucine (Ile) is a precursor for the biosynthesis of anteiso-fatty acids in rat skin, and among the four possible stereoisomers of Ile, L-Ile, and L-allo-Ile were selectively used for biosynthesis of anteiso-fatty acids. This study examined the optical rotation of anteiso-fatty acid derived from DL-Ile to ascertain its stereoconfiguration. Specific rotation of anteiso-fatty acid derived from DL-Ile favorably compared with that derived from L-Ile, suggesting the selective biosynthesis of the (S)-enantiomer of anteiso-fatty acid in rat skin.
