Julian T M
Department of Obstetrics and Gynecology, University of Wisconsin Medical School, Madison, USA.
Am J Obstet Gynecol. 1996 Dec;175(6):1472-5. doi: 10.1016/s0002-9378(96)70092-3.
The study assesses the efficacy and complications of Marlex mesh in repairing severe recurrent anterior vaginal wall prolapse.
Twenty-four patients with two or more postsurgical recurrences of severe anterior vaginal wall prolapse were divided into control and treatment groups. Transvaginal repair was similar between groups except for reinforcement of the anterior vaginal wall with synthetic mesh. Two examiners graded preoperative and postoperative support over the following 2 years (K = 0.9). Fisher's exact test, log-linear analysis, and analysis of variance were used to compare categoric and continuous variables.
Four patients in the control group and none in the treatment group had recurrent anterior vaginal wall prolapse (p < 0.05). Three patients had mesh-related complications.
Repair with a synthetic mesh decreased the expected incidence of severe recurrent anterior vaginal prolapse but was associated with common complications related to synthetic mesh. Mesh reinforcement is an effective treatment for severe recurrent prolapse of the anterior midvaginal wall.
本研究评估了Marlex网片修复严重复发性阴道前壁脱垂的疗效及并发症。
24例有两次或更多次严重阴道前壁脱垂术后复发的患者被分为对照组和治疗组。除了用合成网片加固阴道前壁外，两组的经阴道修复方法相似。两名检查人员在接下来的2年里对术前和术后的支撑情况进行分级（K = 0.9）。采用Fisher精确检验、对数线性分析和方差分析来比较分类变量和连续变量。
对照组有4例患者出现复发性阴道前壁脱垂，治疗组无（p < 0.05）。3例患者出现与网片相关的并发症。
使用合成网片修复降低了严重复发性阴道前壁脱垂的预期发生率，但与合成网片相关的常见并发症有关。网片加固是治疗严重复发性阴道中前壁脱垂的有效方法。
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