Cairns J, Théroux P, Armstrong P, Bogaty P, Kells C, Thompson C, Warnica W
McMaster University, Hamilton, Ontario.
Can J Cardiol. 1996 Dec;12(12):1279-92.
Unstable angina is generally considered to encompass a spectrum of symptomatic manifestations of ischemic heart disease, intermediate between stable angina and acute myocardial infarction. Approximately 75,000 Canadians are hospitalized yearly with unstable angina. The pathophysiology of unstable angina is still imperfectly understood, but is related to the same pathophysiological factors underlying myocardial infarction and sudden cardiac death. In March 1995 a group of Canadian cardiologists met to review the current understanding of unstable angina and to define a Canadian approach to this common problem. Important issues and questions regarding the diagnosis and management of unstable angina were defined. The objective was to outline approaches to the management of unstable angina that would be appropriate in Canada. Topics discussed included definition, incidence, clinical presentations, pathophysiology, initial diagnostic and risk stratification approaches, acute medical management, role of invasive interventions and long term management.
不稳定型心绞痛通常被认为涵盖了一系列缺血性心脏病的症状表现，介于稳定型心绞痛和急性心肌梗死之间。每年约有7.5万加拿大人因不稳定型心绞痛住院。不稳定型心绞痛的病理生理学仍未完全明确，但与心肌梗死和心源性猝死的潜在病理生理因素相关。1995年3月，一群加拿大心脏病专家齐聚一堂，回顾对不稳定型心绞痛的当前认识，并确定加拿大针对这一常见问题的处理方法。明确了有关不稳定型心绞痛诊断和管理的重要问题。目的是概述在加拿大适用的不稳定型心绞痛管理方法。讨论的主题包括定义、发病率、临床表现、病理生理学、初始诊断和风险分层方法、急性药物治疗、侵入性干预措施的作用以及长期管理。
