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微生物植酸酶对猪体内镉蓄积的影响。

Effect of microbial phytase on cadmium accumulation in pigs.

作者信息

Rimbach G, Pallauf J, Walz O P

机构信息

Institute of Animal Nutrition and Nutritional Physiology, Justus Liebig University Giessen, Germany.

出版信息

Arch Tierernahr. 1996;49(4):279-86. doi: 10.1080/17450399609381890.

DOI:10.1080/17450399609381890
PMID:8988314
Abstract

2 x 6 pigs continuously housed in metabolic cages from 25-100 kg weight were fed N-reduced diets based on barley, maize and soybean meal. Diet I (control) contained in FM (fresh matter) 0.56%, 0.48% and 0.46% P (feeding phases A: 25-50 kg, B: 50-75 kg, C: 75-100 kg weight) and 0.76%, 0.71% and 0.68% Ca. Diet II was low in P (0.46%, 0.40%, 0.32%) and Ca (0.69%, 0.62%, 0.52%) and 800 U Aspergillus-phytase per kg were added. Analyzed cadmium concentrations in diet I were 23.4, 19.9 and 13.7 micrograms/kg FM and 20.6, 14.9 and 12.7 micrograms/kg FM in diet II respectively. At 100 kg weight in both treatment groups low cadmium concentrations in liver (11.8 vs. 17.3 micrograms Cd/kg FM) and kidneys (59.6 vs. 102 micrograms Cd/kg FM) were found. Contrary to findings for rats fed semisynthetic diets enriched with high CdCl2 levels, phytase supplementation to the P- and Ca-reduced pig diet with a low Cd concentration significantly enhanced liver and kidney cadmium accumulation. Differences in dietary Cd levels, the binding form of Cd in the diets and the duration of the experimental trials may partially explain the differences found between rats and pigs. Complex interactions between cadmium and various elements, especially calcium, might also have additionally influenced the carry over of cadmium in the present study. Irrespective of the dietary treatment, liver and kidney cadmium concentrations in both groups were considerably lower than maximal permitted values.

摘要

将2×6头猪从体重25千克饲养至100千克,期间持续饲养在代谢笼中,给它们喂食以大麦、玉米和豆粕为基础的低氮日粮。日粮I(对照)的新鲜物质中磷含量分别为0.56%、0.48%和0.46%(饲喂阶段A:25 - 50千克,B:50 - 75千克,C:75 - 100千克体重),钙含量分别为0.76%、0.71%和0.68%。日粮II的磷(0.46%、0.40%、0.32%)和钙(0.69%、0.62%、0.52%)含量较低,每千克添加800单位的黑曲霉植酸酶。日粮I中分析得出的镉浓度分别为23.4、19.9和13.7微克/千克新鲜物质,日粮II中分别为20.6、14.9和12.7微克/千克新鲜物质。在两个处理组猪体重达到100千克时,发现肝脏(11.8对17.3微克镉/千克新鲜物质)和肾脏(59.6对102微克镉/千克新鲜物质)中的镉浓度较低。与喂食富含高浓度氯化镉的半合成日粮的大鼠的研究结果相反,在低镉浓度的低磷低钙猪日粮中添加植酸酶显著提高了肝脏和肾脏中的镉积累量。日粮镉水平的差异、日粮中镉的结合形式以及试验持续时间可能部分解释了大鼠和猪之间的差异。镉与各种元素,尤其是钙之间的复杂相互作用,在本研究中可能也额外影响了镉的留存。无论日粮处理如何,两组的肝脏和肾脏镉浓度均远低于最大允许值。

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