Möller J C, Sautter J, Kupsch A
Department of Neurology, University of Munich, Federal Republic of Germany.
J Neural Transm Suppl. 1996;48:103-12. doi: 10.1007/978-3-7091-7494-4_10.
Neurotrophic factors of dopaminergic neurons may represent a potential neuroprotective therapy for PD. This article reviews published experiments that demonstrate the effects of neurotrophic factors on dopaminergic neurons in vitro and in vivo. At present this issue is predominantly investigated in basic neuroscientific research. Its possible future clinical relevance is discussed.
多巴胺能神经元的神经营养因子可能是帕金森病一种潜在的神经保护疗法。本文回顾了已发表的实验,这些实验证明了神经营养因子在体外和体内对多巴胺能神经元的作用。目前,这个问题主要在基础神经科学研究中进行探讨。文中还讨论了其未来可能的临床相关性。