Chintagumpala M M, Armstrong D, Miki S, Nelson T, Cheek W, Laurent J, Woo S Y, Mahoney D H
Department of Pediatrics, Baylor College of Medicine, Houston, Tex., USA.
Pediatr Neurosurg. 1996 Jun;24(6):306-13. doi: 10.1159/000121060.
Mixed tumors account for about 10% of the childhood central nervous system tumors. Studies of the most common tumor, the ganglioglioma, in patients of all ages suggest that optimal therapy is total gross resection. There are few studies on these tumors in children. In our institution between 1984 and 1993, 28 children with gangliogliomas (4 of which were anaplastic) and 4 children with dysembryoplastic neuroepithelial tumors were treated and followed. Fourteen had local subarachnoid involvement. Total gross resection was usually curative, regardless of histology. Subarachnoid involvement was not indicative of a poorer prognosis.
混合性肿瘤约占儿童中枢神经系统肿瘤的10%。对各年龄段患者中最常见的肿瘤——神经节胶质瘤的研究表明，最佳治疗方法是全瘤大体切除。关于儿童这些肿瘤的研究很少。1984年至1993年间，我们机构治疗并随访了28例神经节胶质瘤患儿（其中4例为间变性）和4例胚胎发育不良性神经上皮肿瘤患儿。14例有局部蛛网膜受累。无论组织学类型如何，全瘤大体切除通常可治愈。蛛网膜受累并不预示预后较差。
