紫丁香苷4-O-β-葡萄糖苷，一种新的苯丙素苷，以及木香烯内酯，一种一氧化氮合酶抑制剂，来自日本厚朴的茎皮。
Syringin 4-O-beta-glucoside, a new phenylpropanoid glycoside, and costunolide, a nitric oxide synthase inhibitor, from the stem bark of Magnolia sieboldii.
作者信息
Park H J, Jung W T, Basnet P, Kadota S, Namba T
机构信息
Department of Botanical Resources, Sangji University, Wonju, Korea.
出版信息
J Nat Prod. 1996 Dec;59(12):1128-30. doi: 10.1021/np960452i.
PMID:8988596
Abstract
Syringin 4-O-beta-glucoside (1), a new phenylpropanoid glycoside, and costunolide (2) were isolated from the stem bark of Magnolia sieboldii. The structures were determined by spectroscopic and chemical methods. Costunolide (2) exhibited strong nitric oxide synthase inhibitory activity in the endotoxin-activated murine macrophage, J774.1.
摘要
紫丁香苷4-O-β-葡萄糖苷（1），一种新的苯丙素苷，以及木香烃内酯（2）从日本厚朴的茎皮中分离得到。通过光谱和化学方法确定了其结构。木香烃内酯（2）在内毒素激活的小鼠巨噬细胞J774.1中表现出较强的一氧化氮合酶抑制活性。
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