Osborne M L, Vollmer W M, Buist A S
Department of Medicine, Oregon Health Sciences University, Portland, USA.
Chest. 1996 Dec;110(6):1458-62. doi: 10.1378/chest.110.6.1458.
Since seasonal patterns in morbidity may identify triggers provoking hospital-based care for airflow obstruction, this study examined seasonal variation in patterns of hospitalizations for asthma, chronic bronchitis, and emphysema.
The data for this analysis were derived from the abstracted medical records of a large health maintenance organization, Kaiser Permanente, Northwest region, over the period 1979 to 1987.
In all, 2,060 primary hospital discharges for asthma and 1,121 primary hospital discharges for the combination chronic bronchitis/emphysema were observed.
The monthly patterns varied for asthma and chronic bronchitis/emphysema, and also varied by age and sex. For young children 0 to 14 years, asthma hospitalizations peaked primarily in the fall. In contrast, for young children 0 to 14 years, hospitalizations for chronic bronchitis/ emphysema peaked in the fall/winter months. Seasonal variation decreased as age increased for chronic bronchitis/emphysema, such that for the 65+ year group, there was no seasonal variation.
A better understanding of the causes of the age-specific seasonal patterns in these obstructive respiratory diseases may help to reduce the morbidity that is associated with them.
由于发病率的季节性模式可能识别引发气流阻塞住院治疗的触发因素，本研究调查了哮喘、慢性支气管炎和肺气肿住院模式的季节性变化。
本分析的数据来自1979年至1987年期间大型健康维护组织西北地区凯撒医疗集团的摘要病历。
总共观察到2060例哮喘患者的首次住院出院病例以及1121例慢性支气管炎/肺气肿患者的首次住院出院病例。
哮喘和慢性支气管炎/肺气肿的月度模式各不相同，且因年龄和性别而异。对于0至14岁的幼儿，哮喘住院率主要在秋季达到峰值。相比之下，对于0至14岁的幼儿，慢性支气管炎/肺气肿的住院率在秋冬季节达到峰值。慢性支气管炎/肺气肿的季节性变化随着年龄增长而减小，因此对于65岁及以上年龄组，没有季节性变化。
更好地了解这些阻塞性呼吸道疾病特定年龄季节性模式的原因可能有助于降低与之相关的发病率。
